Dataset Information
Aberrant paralimbic gray matter in incarcerated male adolescents with psychopathic traits.
Ontology highlight
ABSTRACT: Objective
To investigate the relationship between brain structure and psychopathic traits in maximum-security incarcerated male adolescents, and to examine whether the associations between brain volumes in paralimbic and limbic regions and psychopathic traits observed in incarcerated adult men extend to an independent sample of incarcerated male adolescents.Method
A structural magnetic resonance imaging (MRI) study of regional gray matter volumes by using voxel-based morphometry in maximum-security incarcerated male adolescents (N = 218) assessed for psychopathic traits using the Hare Psychopathy Checklist-Youth Version (PCL-YV). All analyses controlled for effects of age, substance use, and brain size.Results
Consistent with hypotheses and the adult literature, psychopathic traits were associated with decreased regional gray matter volumes in diffuse paralimbic regions, including orbitofrontal cortex, bilateral temporal poles, and posterior cingulate cortex.Conclusions
These results strengthen the interpretation that paralimbic regions are central for understanding neural dysfunction associated with psychopathic traits and that psychopathy is best conceptualized as a neurodevelopmental disorder.
SUBMITTER: Ermer E
PROVIDER: S-EPMC3549663 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Publications
Aberrant paralimbic gray matter in incarcerated male adolescents with psychopathic traits.
Journal of the American Academy of Child and Adolescent Psychiatry 20130101 1
<h4>Objective</h4>To investigate the relationship between brain structure and psychopathic traits in maximum-security incarcerated male adolescents, and to examine whether the associations between brain volumes in paralimbic and limbic regions and psychopathic traits observed in incarcerated adult men extend to an independent sample of incarcerated male adolescents.<h4>Method</h4>A structural magnetic resonance imaging (MRI) study of regional gray matter volumes by using voxel-based morphometry ...[more]