Ontology highlight
ABSTRACT:
SUBMITTER: Ryckman KK
PROVIDER: S-EPMC3552557 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Journal of pediatric endocrinology & metabolism : JPEM 20120101 3-4
Nationally, newborn screening programs use 17-hydroxyprogesterone (17-OHP) as the biomarker to detect the rare but potentially fatal inherited disease, congenital adrenal hyperplasia. However, this biomarker is highly variable, with a high false-positive rate of detection, particularly in neonates born preterm. Several studies have examined various clinical and genetic factors to explain the variability of 17-OHP in preterm infants. The purpose of this study was to replicate previous clinical an ...[more]