Ontology highlight
ABSTRACT:
SUBMITTER: Pascolo L
PROVIDER: S-EPMC3553542 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Pascolo Lorella L Gianoncelli Alessandra A Schneider Giulia G Salomé Murielle M Schneider Manuela M Calligaro Carla C Kiskinova Maya M Melato Mauro M Rizzardi Clara C
Scientific reports 20130124
Asbestos is a potent carcinogen associated with malignant mesothelioma and lung cancer but its carcinogenic mechanisms are still poorly understood. Asbestos toxicity is ascribed to its particular physico-chemical characteristics, and one of them is the presence of and ability to adsorb iron, which may cause an alteration of iron homeostasis in the tissue. This observational study reports a combination of advanced synchrotron-based X-ray imaging and micro-spectroscopic methods that provide correl ...[more]