Ontology highlight
ABSTRACT:
SUBMITTER: Chattopadhyay PK
PROVIDER: S-EPMC3554182 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Chattopadhyay Pratip K PK Chelimo Kiprotich K Embury Paula B PB Mulama David H DH Sumba Peter Odada PO Gostick Emma E Ladell Kristin K Brodie Tess M TM Vulule John J Roederer Mario M Moormann Ann M AM Price David A DA
Journal of virology 20121121 3
Coinfection with Plasmodium falciparum malaria and Epstein-Barr virus (EBV) is a major risk factor for endemic Burkitt lymphoma (eBL), still one of the most prevalent pediatric cancers in equatorial Africa. Although malaria infection has been associated with immunosuppression, the precise mechanisms that contribute to EBV-associated lymphomagenesis remain unclear. In this study, we used polychromatic flow cytometry to characterize CD8(+) T-cell subsets specific for EBV-derived lytic (BMFL1 and B ...[more]