Ontology highlight
ABSTRACT:
SUBMITTER: Wistow G
PROVIDER: S-EPMC3554465 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Crystallins are the abundant, long-lived proteins of the eye lens. The major human crystallins belong to two different superfamilies: the small heat-shock proteins (α-crystallins) and the βγ-crystallins. During evolution, other proteins have sometimes been recruited as crystallins to modify the properties of the lens. In the developing human lens, the enzyme betaine-homocysteine methyltransferase serves such a role. Evolutionary modification has also resulted in loss of expression of some human ...[more]