Lipid management in the prevention of stroke: a meta-analysis of fibrates for stroke prevention.

ABSTRACT:

Background

Fibrates has been extensively used to improve plasma lipid levels and prevent adverse cardiovascular outcomes. However, the effect of fibrates on stroke is unclear at the present time. We therefore carried out a comprehensive systematic review and meta-analysis to evaluate the effects of fibrates on stroke.

Methods

We systematically searched Medline, Embase, the Cochrane Central Register of Controlled Trials, reference lists of articles, and proceedings of major meetings to identify studies for our analysis. We included randomized placebo controlled trials which reported the effects of fibrates on stroke. Relative risk (RR) was used to measure the effect of fibrates on the risk of stroke under random effect model. The analysis was further stratified by factors tha

SUBMITTER: Zhou YH 

PROVIDER: S-EPMC3554504 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature