Ontology highlight
ABSTRACT:
SUBMITTER: Lu Y
PROVIDER: S-EPMC3555137 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Lu Yanbing Y Yin Lichen L Zhang Yanfeng Y Zhonghai Zhang Z Xu Yunxiang Y Tong Rong R Cheng Jianjun J
ACS macro letters 20120401 4
O-benzyl-L-serine carboxyanhydrides were synthesized via diazotization of O-benzyl-L-serine with sodium nitrite in aqueous sulfuric acid solution followed by cyclization of the resulting serine-based α-hydroxy acid with phosgene. Degradable, water-soluble poly(α-hydroxy acids) bearing pendant hydroxyl groups were readily prepared under mild conditions via ring-opening polymerization of O-benzyl-L-serine carboxyanhydrides followed by removal of the benzyl group and showed excellent cell compatibi ...[more]