Type 6 secretion dynamics within and between bacterial cells.
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ABSTRACT:
SUBMITTER: Basler M
PROVIDER: S-EPMC3557511 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Publications
Type 6 secretion dynamics within and between bacterial cells.
Science (New York, N.Y.) 20120705 6096
The bacterial type 6 secretion system (T6SS) functions as a virulence factor capable of attacking both eukaryotic and prokaryotic target cells by a process that involves protein transport through a contractile bacteriophage tail-like structure. The T6SS apparatus is composed, in part, of an exterior sheath wrapped around an interior tube. Here, we report that in living cells the cytoplasmic adenosine triphosphatase called ClpV specifically recognizes the contracted T6SS sheath structure, causing ...[more]
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