Ontology highlight
ABSTRACT:
SUBMITTER: Broussard GW
PROVIDER: S-EPMC3557535 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Broussard Gregory W GW Oldfield Lauren M LM Villanueva Valerie M VM Lunt Bryce L BL Shine Emilee E EE Hatfull Graham F GF
Molecular cell 20121213 2
Genetic switches are critical components of developmental circuits. Because temperate bacteriophages are vastly abundant and greatly diverse, they are rich resources for understanding the mechanisms and evolution of switches and the molecular control of genetic circuitry. Here, we describe a new class of small, compact, and simple switches that use site-specific recombination as the key decision point. The phage attachment site attP is located within the phage repressor gene such that chromosoma ...[more]