Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis.

ABSTRACT:

Objective

To assess for the presence of a sex interaction in the associations of estimated glomerular filtration rate and albuminuria with all-cause mortality, cardiovascular mortality, and end stage renal disease.

Design

Random effects meta-analysis using pooled individual participant data.

Setting

46 cohorts from Europe, North and South America, Asia, and Australasia.

Participants

2,051,158 participants (54% women) from general population cohorts (n=1,861,052), high risk cohorts (n=151,494), and chronic kidney disease cohorts (n=38,612). Eligible cohorts (except chronic kidney disease cohorts) had at least 1000 participants, outcomes of either mortality or end stage renal disease of ≥ 50 events, and baseline measurements of estimated glomerular filtration rat

SUBMITTER: Nitsch D 

PROVIDER: S-EPMC3558410 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature