Ontology highlight
ABSTRACT:
SUBMITTER: Goode EL
PROVIDER: S-EPMC3559692 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Goode Ellen L EL DeRycke Melissa M Kalli Kimberly R KR Oberg Ann L AL Cunningham Julie M JM Maurer Matthew J MJ Fridley Brooke L BL Armasu Sebastian M SM Serie Daniel J DJ Ramar Priya P Goergen Krista K Vierkant Robert A RA Rider David N DN Sicotte Hugues H Wang Chen C Winterhoff Boris B Phelan Catherine M CM Schildkraut Joellen M JM Weber Rachel P RP Iversen Ed E Berchuck Andrew A Sutphen Rebecca R Birrer Michael J MJ Hampras Shalaka S Preus Leah L Gayther Simon A SA Ramus Susan J SJ Wentzensen Nicolas N Yang Hannah P HP Garcia-Closas Montserrat M Song Honglin H Tyrer Jonathan J Pharoah Paul P D PP Konecny Gottfried G Sellers Thomas A TA Ness Roberta B RB Sucheston Lara E LE Odunsi Kunle K Hartmann Lynn C LC Moysich Kirsten B KB Knutson Keith L KL
PloS one 20130130 1
Although ovarian cancer is the most lethal of gynecologic malignancies, wide variation in outcome following conventional therapy continues to exist. The presence of tumor-infiltrating regulatory T cells (Tregs) has a role in outcome of this disease, and a growing body of data supports the existence of inherited prognostic factors. However, the role of inherited variants in genes encoding Treg-related immune molecules has not been fully explored. We analyzed expression quantitative trait loci (eQ ...[more]