Ontology highlight
ABSTRACT:
SUBMITTER: Flynn KE
PROVIDER: S-EPMC3559741 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Flynn Kathryn E KE Hahn Cynthia L CL Kramer Judith M JM Check Devon K DK Dombeck Carrie B CB Bang Soo S Perlmutter Jane J Khin-Maung-Gyi Felix A FA Weinfurt Kevin P KP
PloS one 20130130 1
Research institutions differ in their willingness to defer to a single, central institutional review board (IRB) for multicenter clinical trials, despite statements from the FDA, OHRP, and NIH in support of using central IRBs to improve the efficiency of conducting trials. The Clinical Trials Transformation Initiative (CTTI) supported this project to solicit current perceptions of barriers to the use of central IRBs and to formulate potential solutions. We held discussions with IRB experts, inte ...[more]