Ontology highlight
ABSTRACT:
SUBMITTER: Ullah G
PROVIDER: S-EPMC3560535 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Ullah Ghanim G Parker Ian I Mak Don-On Daniel DO Pearson John E JE
Cell calcium 20120606 2
The spatiotemporal dynamics of elementary Ca(2+) release events, such as "blips" and "puffs" shapes the hierarchal Ca(2+) signaling in many cell types. Despite being the building blocks of Ca(2+) patterning, the mechanism responsible for the observed properties of puffs, especially their termination is incompletely understood. In this paper, we employ a data-driven approach to gain insights into the complex dynamics of blips and puffs. We use a model of inositol 1,4,5-trisphosphate (IP(3)) recep ...[more]