Ontology highlight
ABSTRACT:
SUBMITTER: Yu CC
PROVIDER: S-EPMC3561343 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Yu Cheng-Chou CC Yang Jyh-Chin JC Chang Yen-Ching YC Chuang Jiing-Guang JG Lin Chung-Wu CW Wu Ming-Shiang MS Chow Lu-Ping LP
PloS one 20130131 1
Previous studies have demonstrated that valosin-containing protein (VCP) is associated with H. pylori-induced gastric carcinogenesis. By identifying the interactome of VCP overexpressed in AGS cells using a subtractive proteomics approach, we aimed to characterize the cellular responses mediated by VCP and its functional roles in H. pylori-associated gastric cancer. VCP immunoprecipitations followed by proteomic analysis identified 288 putative interacting proteins, 18 VCP-binding proteins belon ...[more]