Synthesis of biotinylated c-di-gmp and c-di-amp using click conjugation.
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ABSTRACT:
SUBMITTER: Gaffney BL
PROVIDER: S-EPMC3561633 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
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Synthesis of biotinylated c-di-gmp and c-di-amp using click conjugation.
Gaffney Barbara L BL Stebbins Nicholas D ND Jones Roger A RA
Nucleosides, nucleotides & nucleic acids 20130101 1
The biotinylated c-di-GMP and c-di-AMP conjugates 10a/b were synthesized by a straightforward set of procedures from standard, commercially available phosphoramidites. Their availability should allow isolation and characterization of new protein and RNA receptors for these key bacterial signaling molecules. ...[more]
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