Dataset Information
RetroSeq: transposable element discovery from next-generation sequencing data.
Ontology highlight
ABSTRACT: Unlabelled
A significant proportion of eukaryote genomes consist of transposable element (TE)-derived sequence. These elements are known to have the capacity to modulate gene function and genome evolution. We have developed RetroSeq for detecting non-reference TE insertions from Illumina paired-end whole-genome sequencing data. We evaluate RetroSeq on a human trio from the 1000 Genomes Project, showing that it produces highly accurate TE calls.Availabilty
RetroSeq is open-source and available from https://github.com/tk2/RetroSeq.
SUBMITTER: Keane TM
PROVIDER: S-EPMC3562067 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Publications
RetroSeq: transposable element discovery from next-generation sequencing data.
Bioinformatics (Oxford, England) 20121210 3
A significant proportion of eukaryote genomes consist of transposable element (TE)-derived sequence. These elements are known to have the capacity to modulate gene function and genome evolution. We have developed RetroSeq for detecting non-reference TE insertions from Illumina paired-end whole-genome sequencing data. We evaluate RetroSeq on a human trio from the 1000 Genomes Project, showing that it produces highly accurate TE calls.<h4>Availabilty</h4>RetroSeq is open-source and available from ...[more]
