Ontology highlight
ABSTRACT:
SUBMITTER: Gudmundsson J
PROVIDER: S-EPMC3562711 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Nature genetics 20121028 12
In Western countries, prostate cancer is the most prevalent cancer of men and one of the leading causes of cancer-related death in men. Several genome-wide association studies have yielded numerous common variants conferring risk of prostate cancer. Here, we analyzed 32.5 million variants discovered by whole-genome sequencing 1,795 Icelanders. We identified a new low-frequency variant at 8q24 associated with prostate cancer in European populations, rs188140481[A] (odds ratio (OR) = 2.90; P(combi ...[more]