Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis.

ABSTRACT:

Background

There is an increased risk of venous thromboembolism among women taking oral contraceptives. However, whether there is an additional risk among women with polycystic ovary syndrome (PCOS) is unknown.

Methods

We developed a population-based cohort from the IMS LifeLink Health Plan Claims Database, which includes managed care organizations in the United States. Women aged 18-46 years taking combined oral contraceptives and who had a claim for PCOS (n = 43 506) were matched, based on a propensity score, to control women (n = 43 506) taking oral contraceptives. Venous thromboembolism was defined using administrative coding and use of anticoagulation. We used Cox proportional hazards models to assess the relative risk (RR) of venous thromboembolism among users of combi

SUBMITTER: Bird ST 

PROVIDER: S-EPMC3563911 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature