Dataset Information

Ozone oxidation of antidepressants in wastewater -Treatment evaluation and characterization of new by-products by LC-QToFMS.

ABSTRACT:

Unlabelled

Background

The fate of 14 antidepressants along with their respective N-desmethyl metabolites and the anticonvulsive drug carbamazepine was examined in a primary sewage treatment plant (STP) and following advanced treatments with ozone (O3). The concentrations of each pharmaceutical compound were determined in raw sewage, effluent and sewage sludge samples by LC-MS/MS analysis. The occurrence of antidepressant by-products formed in treated effluent after ozonation was also investigated.

Results

Current primary treatments using physical and chemical processes removed little of the compounds (mean removal efficiency: 19%). Experimental sorption coefficients (Kd) of each studied compounds were also calculated. Sorption of venlafaxine, desmethylvenlafaxine, and carbamazepine on sludge was assumed to be negligible (log Kd ? 2), but higher sorption behavior can be expected for sertraline (log Kd ? 4). Ozonation treatment with O3 (5 mg/L) led to a satisfactory mean removal efficiency of 88% of the compounds. Screening of the final ozone-treated effluent samples by high resolution-mass spectrometry (LC-QqToFMS) did confirm the presence of related N-oxide by-products.

Conclusion

Effluent ozonation led to higher mean removal efficiencies than current primary treatment, and therefore represented a promising strategy for the elimination of antidepressants in urban wastewaters. However, the use of O3 produced by-products with unknown toxicity.

SUBMITTER: Lajeunesse A

PROVIDER: S-EPMC3564768 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature

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Publications

Ozone oxidation of antidepressants in wastewater -Treatment evaluation and characterization of new by-products by LC-QToFMS.

Lajeunesse André A Blais Mireille M Barbeau Benoît B Sauvé Sébastien S Gagnon Christian C

Chemistry Central journal 20130125 1

<h4>Unlabelled</h4><h4>Background</h4>The fate of 14 antidepressants along with their respective N-desmethyl metabolites and the anticonvulsive drug carbamazepine was examined in a primary sewage treatment plant (STP) and following advanced treatments with ozone (O3). The concentrations of each pharmaceutical compound were determined in raw sewage, effluent and sewage sludge samples by LC-MS/MS analysis. The occurrence of antidepressant by-products formed in treated effluent after ozonation was ...[more]

PMID: 23351428

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Dataset Information

Ozone oxidation of antidepressants in wastewater -Treatment evaluation and characterization of new by-products by LC-QToFMS.

Unlabelled

Background

Results

Conclusion

Publications

Ozone oxidation of antidepressants in wastewater -Treatment evaluation and characterization of new by-products by LC-QToFMS.

Similar Datasets

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