Ontology highlight
ABSTRACT:
SUBMITTER: Stokes MP
PROVIDER: S-EPMC3565264 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Stokes Matthew P MP Silva Jeffrey C JC Jia Xiaoying X Lee Kimberly A KA Polakiewicz Roberto D RD Comb Michael J MJ
International journal of molecular sciences 20121221 1
Traditional methods for analysis of peptides using liquid chromatography and tandem mass spectrometry (LC-MS/MS) lack the specificity to comprehensively monitor specific biological processes due to the inherent duty cycle limitations of the MS instrument and the stochastic nature of the analytical platform. PTMScan Direct is a novel, antibody-based method that allows quantitative LC-MS/MS profiling of specific peptides from proteins that reside in the same signaling pathway. New PTMScan Direct r ...[more]