Ontology highlight
ABSTRACT:
SUBMITTER: Awwad K
PROVIDER: S-EPMC3565439 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Awwad Khaldeyah K Desai Anna A Smith Clyde C Sommerhalter Monika M
Acta crystallographica. Section D, Biological crystallography 20130118 Pt 2
The hyperthermophilic bacterium Thermotoga maritima has a noncanonical nucleoside triphosphatase that catalyzes the conversion of inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) and xanthosine triphosphate (XTP) into inosine monophosphate (IMP), deoxyinosine monophosphate (IMP) and xanthosine monophosphate (XMP), respectively. The k(cat)/K(m) values determined at 323 and 353 K fall between 1.31 × 10(4) and 7.80 × 10(4) M(-1) s(-1). ITP and dITP are slightly preferred over XTP. Activ ...[more]