Ontology highlight
ABSTRACT:
SUBMITTER: Chang J
PROVIDER: S-EPMC3565951 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Chang Jie J Oikawa Shinji S Ichihara Gaku G Nanpei Yui Y Hotta Yasuhiro Y Yamada Yoshiji Y Tada-Oikawa Saeko S Iwahashi Hitoshi H Kitagawa Emiko E Takeuchi Ichiro I Yuda Masao M Ichihara Sahoko S
Nutrition & metabolism 20120921 1
<h4>Unlabelled</h4><h4>Background</h4>It is difficult to study the mechanisms of the metabolic syndrome in humans due to the heterogeneous genetic background and lifestyle. The present study investigated changes in the gene and protein profiles in an animal model of the metabolic syndrome to identify the molecular targets associated with the pathogenesis and progression of obesity related to the metabolic syndrome.<h4>Methods</h4>We extracted mRNAs and proteins from the liver tissues of 6- and 2 ...[more]