Ontology highlight
ABSTRACT:
SUBMITTER: Dreifuss AA
PROVIDER: S-EPMC3567083 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Dreifuss Arturo Alejandro AA Bastos-Pereira Amanda Leite AL Fabossi Isabella Aviles IA Lívero Francislaine Aparecida Dos Reis FA Stolf Aline Maria AM Alves de Souza Carlos Eduardo CE Gomes Liana de Oliveira Lde O Constantin Rodrigo Polimeni RP Furman Aline Emmer Ferreira AE Strapasson Regiane Lauriano Batista RL Teixeira Simone S Zampronio Aleksander Roberto AR Muscará Marcelo Nicolás MN Stefanello Maria Elida Alves ME Acco Alexandra A
PloS one 20130207 2
This study aimed to compare the anti-neoplastic effects of an Uncaria tomentosa (UT) brute hydroethanolic (BHE) extract with those of two fractions derived from it. These fractions are choroformic (CHCl3) and n-butanolic (BuOH), rich in pentacyclic oxindole alkaloids (POA) and antioxidant substances, respectively. The cancer model was the subcutaneous inoculation of Walker-256 tumour cells in the pelvic limb of male Wistar rat. Subsequently to the inoculation, gavage with BHE extract (50 mg.kg(- ...[more]