Ontology highlight
ABSTRACT:
SUBMITTER: Longo LM
PROVIDER: S-EPMC3568330 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Longo Liam M LM Lee Jihun J Blaber Michael M
Proceedings of the National Academy of Sciences of the United States of America 20130122 6
A compendium of different types of abiotic chemical syntheses identifies a consensus set of 10 "prebiotic" α-amino acids. Before the emergence of biosynthetic pathways, this set is the most plausible resource for protein formation (i.e., proteogenesis) within the overall process of abiogenesis. An essential unsolved question regarding this prebiotic set is whether it defines a "foldable set"--that is, does it contain sufficient chemical information to permit cooperatively folding polypeptides? I ...[more]