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First molecular identification of human Dobrava virus infection in central Europe.

ABSTRACT: Viral RNA was amplified by reverse transcription-PCR from a patient suffering from hemorrhagic fever with renal syndrome (HFRS) in Germany. The virus strain could be assigned to the Dobrava hantavirus (DOBV). This is the first molecular identification of human infection by DOBV in central Europe and the first proof that a virus strain related to the DOBV-Aa lineage, carried by Apodemus agrarius rodents, is able to cause HFRS.

SUBMITTER: Klempa B

PROVIDER: S-EPMC356881 | biostudies-literature | 2004 Mar

REPOSITORIES: biostudies-literature

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First molecular identification of human Dobrava virus infection in central Europe.

Klempa Boris B Schütt Morten M Auste Brita B Labuda Milan M Ulrich Rainer R Meisel Helga H Krüger Detlev H DH

Journal of clinical microbiology 20040301 3

Viral RNA was amplified by reverse transcription-PCR from a patient suffering from hemorrhagic fever with renal syndrome (HFRS) in Germany. The virus strain could be assigned to the Dobrava hantavirus (DOBV). This is the first molecular identification of human infection by DOBV in central Europe and the first proof that a virus strain related to the DOBV-Aa lineage, carried by Apodemus agrarius rodents, is able to cause HFRS. ...[more]

PMID: 15004109

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