Ontology highlight
ABSTRACT:
SUBMITTER: Vergani A
PROVIDER: S-EPMC3569513 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Vergani Andrea A Tezza Sara S D'Addio Francesca F Fotino Carmen C Liu Kaifeng K Niewczas Monika M Bassi Roberto R Molano R Damaris RD Kleffel Sonja S Petrelli Alessandra A Soleti Antonio A Ammirati Enrico E Frigerio Maria M Visner Gary G Grassi Fabio F Ferrero Maria E ME Corradi Domenico D Abdi Reza R Ricordi Camillo C Sayegh Mohamed H MH Pileggi Antonello A Fiorina Paolo P
Circulation 20121218 4
<h4>Background</h4>Heart transplantation is a lifesaving procedure for patients with end-stage heart failure. Despite much effort and advances in the field, current immunosuppressive regimens are still associated with poor long-term cardiac allograft outcomes, and with the development of complications, including infections and malignancies, as well. The development of a novel, short-term, and effective immunomodulatory protocol will thus be an important achievement. The purine ATP, released duri ...[more]