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N-(5-Amino-1H-1,2,4-triazol-3-yl)pyridine-2-carboxamide.

ABSTRACT: The title compound, C(8)H(8)N(6)O, was obtained by the reaction of 3,5-diamino-1,2,4-triazole with ethyl 2-picolinate in a glass oven. The dihedral angles formed between the plane of the amide group and the pyridine and triazole rings are 11.8?(3) and 5.8?(3)°, respectively. In the crystal, an extensive system of classical N-H?N and N-H?O hydrogen bonds generate an infinite three-dimensional network.

SUBMITTER: Hernandez-Gil J

PROVIDER: S-EPMC3569762 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature

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N-(5-Amino-1H-1,2,4-triazol-3-yl)pyridine-2-carboxamide.

Hernández-Gil Javier J Ferrer Sacramento S Ballesteros Rafael R Castiñeiras Alfonso A

Acta crystallographica. Section E, Structure reports online 20130112 Pt 2

The title compound, C(8)H(8)N(6)O, was obtained by the reaction of 3,5-diamino-1,2,4-triazole with ethyl 2-picolinate in a glass oven. The dihedral angles formed between the plane of the amide group and the pyridine and triazole rings are 11.8 (3) and 5.8 (3)°, respectively. In the crystal, an extensive system of classical N-H⋯N and N-H⋯O hydrogen bonds generate an infinite three-dimensional network. ...[more]

PMID: 23424508

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Syntheses of Novel 4-Substituted N-(5-amino-1H-1,2,4-triazol-3-yl)pyridine-3-sulfonamide Derivatives with Potential Antifungal Activity.

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