Ontology highlight
ABSTRACT:
SUBMITTER: Gasche JA
PROVIDER: S-EPMC3569850 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Future oncology (London, England) 20121101 11
Dysregulation of gene expression is a frequent occurrence in oral squamous cell carcinoma (OSCC). However, accumulating evidence suggests that in contrast to genetics, epigenetic modifications consisting of aberrant DNA methylation, histone modifications and altered expression of miRNAs induce OSCC tumorigenesis and perhaps play a more central role in the evolution and progression of this disease. The unifying theme among these three epigenetic mechanisms remains the same, which is aberrant regu ...[more]