Dense representation of natural odorants in the mouse olfactory bulb.
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ABSTRACT:
SUBMITTER: Vincis R
PROVIDER: S-EPMC3570072 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Publications
Dense representation of natural odorants in the mouse olfactory bulb.
Vincis Roberto R Gschwend Olivier O Bhaukaurally Khaleel K Beroud Jonathan J Carleton Alan A
Nature neuroscience 20120311 4
In mammals, odorant molecules are thought to activate only a few glomeruli, leading to the hypothesis that odor representation in the olfactory bulb is sparse. However, the studies supporting this model used anesthetized animals or monomolecular odorants at limited concentration ranges. Using optical imaging and two-photon microscopy, we found that natural odorants at their native concentrations could elicit dense representations in the olfactory bulb. Both anesthesia and odorant concentration w ...[more]
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