Ontology highlight
ABSTRACT:
SUBMITTER: Tsushima H
PROVIDER: S-EPMC3570524 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Tsushima Hanako H Malabarba Maria Grazia MG Confalonieri Stefano S Senic-Matuglia Francesca F Verhoef Lisette G G C LG Bartocci Cristina C D'Ario Giovanni G Cocito Andrea A Di Fiore Pier Paolo PP Salcini Anna Elisabetta AE
PloS one 20130212 2
Protein interaction modules coordinate the connections within and the activity of intracellular signaling networks. The Eps15 Homology (EH) module, a protein-protein interaction domain that is a key feature of the EH-network, was originally identified in a few proteins involved in endocytosis and vesicle trafficking, and has subsequently also been implicated in actin reorganization, nuclear shuttling, and DNA repair. Here we report an extensive characterization of the physical connections and of ...[more]