Ontology highlight
ABSTRACT:
SUBMITTER: Wang GD
PROVIDER: S-EPMC3570536 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Wang Guo-dong GD Cheng Lu-guang LG Fan Ruo-xi RX Irwin David M DM Tang Shu-sheng SS Peng Jian-guo JG Zhang Ya-ping YP
PloS one 20130212 2
Coat color in dog breeds is an excellent character for revealing the power of artificial selection, as it is extremely diverse and likely the result of recent domestication. Coat color is generated by melanocytes, which synthesize pheomelanin (a red or yellow pigment) or eumelanin (a black or brown pigment) through the pigment type-switching pathway, and is regulated by three genes in dogs: MC1R (melanocortin receptor 1), CBD103 (β-defensin 103), and ASIP (agouti-signaling protein precursor). Th ...[more]