Ontology highlight
ABSTRACT:
SUBMITTER: Bogdan R
PROVIDER: S-EPMC3570616 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Bogdan Ryan R Nikolova Yuliya S YS Pizzagalli Diego A DA
Neurobiology of disease 20120601
Major depressive disorder (MDD) is etiologically complex and has a heterogeneous presentation. This heterogeneity hinders the ability of molecular genetic research to reliably detect the small effects conferred by common genetic variation. As a result, significant research efforts have been directed at investigating more homogenous intermediate phenotypes believed to be more proximal to gene function and lie between genes and/or environmental effects and disease processes. In the current review ...[more]