Relationship between urinary triclosan and paraben concentrations and serum thyroid measures in NHANES 2007-2008.

ABSTRACT: Triclosan and parabens are broad spectrum antimicrobials used in a range of consumer products. In vitro and animal studies have suggested the potential for these compounds to disrupt thyroid function, though studies in humans have been limited. The objective of the study was to assess the relationship of urinary concentrations of triclosan and parabens with serum thyroid measures in a large, representative sample of the US population. We conducted an exploratory, cross-sectional analysis of data on urinary biomarkers of triclosan and paraben exposure and serum thyroid measures obtained from 1831 subjects (ages≥12 years) as part of the 2007-2008 National Health and Nutrition Examination Survey (NHANES). We found evidence of some inverse associations between parabens and circulating thyroid

SUBMITTER: Koeppe ES 

PROVIDER: S-EPMC3572338 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature