Basal ganglia-cortical interactions in Parkinsonian patients.
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ABSTRACT:
SUBMITTER: Marreiros AC
PROVIDER: S-EPMC3573233 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Publications
Basal ganglia-cortical interactions in Parkinsonian patients.
Marreiros André C AC Cagnan Hayriye H Moran Rosalyn J RJ Friston Karl J KJ Brown Peter P
NeuroImage 20121113
Parkinson's disease is a common and debilitating condition, caused by aberrant activity in a complex basal ganglia-thalamocortical circuit. Therapeutic advances rely on characterising interactions in this circuit. However, recording electrophysiological responses over the entire circuit is impractical. Dynamic causal modelling offers large-scale models of predictive value based on a limited or partial sampling of complex networks. Using dynamic causal modelling, we determined the network changes ...[more]
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