Ontology highlight
ABSTRACT:
SUBMITTER: Arnold SE
PROVIDER: S-EPMC3575080 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Arnold Steven E SE Vega Irving E IE Karlawish Jason H JH Wolk David A DA Nunez Jessica J Negron Mirna M Xie Sharon X SX Wang Li-San LS Dubroff Jacob G JG McCarty-Wood Elisabeth E Trojanowski John Q JQ Van Deerlin Vivianna V
Journal of Alzheimer's disease : JAD 20130101 4
The frequency and clinical and pathological characteristics associated with the Gly206Ala presenilin 1 (PSEN1) mutation in Puerto Rican and non-Puerto Rican Hispanics were evaluated at the University of Pennsylvania's Alzheimer's Disease Center. DNAs from all cohort subjects were genotyped for the Gly206Ala PSEN1 mutation. Carriers and non-carriers with neurodegenerative disease dementias were compared for demographic, clinical, psychometric, and biomarker variables. Nineteen (12.6%) of 151 unre ...[more]