Ontology highlight
ABSTRACT:
SUBMITTER: Yanagida S
PROVIDER: S-EPMC3575586 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Yanagida Satoshi S Taniue Kenzui K Sugimasa Hironobu H Nasu Emiko E Takeda Yasuko Y Kobayashi Mana M Yamamoto Tadashi T Okamoto Aikou A Akiyama Tetsu T
Scientific reports 20130101
Mammalian genomes encode numerous antisense non-coding RNAs, which are assumed to be involved in the regulation of the sense gene expression. However, the mechanisms of their action and involvement in the development of diseases have not been well elucidated. The ANA/BTG3 protein is an antiproliferative protein whose expression is downregulated in prostate and lung cancers. Here we show that an antisense transcript of the ANA/BTG3 gene, termed ASBEL, negatively regulates the levels of ANA/BTG3 p ...[more]