Ontology highlight
ABSTRACT:
SUBMITTER: Watarai S
PROVIDER: S-EPMC3575622 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Watarai Shinobu S Iwase Tana T Tajima Tomoko T Yuba Eiji E Kono Kenji K
TheScientificWorldJournal 20130204
The usefulness of pH-sensitive fusogenic polymer-(succinylated poly(glycidol)-(SucPG-) modified liposomes as a vaccine carrier in the induction of immune responses was evaluated. Mice were intraperitoneally immunized with ovalbumin- (OVA-) containing SucPG-modified liposomes. After immunization, significant OVA-specific antibodies were detected in the serum. When sera were analyzed for isotype distribution, OVA-specific IgG1 antibody responses were noted in mice immunized with OVA-containing pol ...[more]