Ontology highlight
ABSTRACT:
SUBMITTER: Sosinowski T
PROVIDER: S-EPMC3578102 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Sosinowski Tomasz T White Jason T JT Cross Eric W EW Haluszczak Catherine C Marrack Philippa P Gapin Laurent L Kedl Ross M RM
Journal of immunology (Baltimore, Md. : 1950) 20130125 5
Various populations of memory phenotype CD8(+) T cells have been described over the last 15-20 y, all of which possess elevated effector functions relative to naive phenotype cells. Using a technique for isolating Ag-specific cells from unprimed hosts, we recently identified a new subset of cells, specific for nominal Ag, but phenotypically and functionally similar to memory cells arising as a result of homeostatic proliferation. We show in this study that these virtual memory (VM) cells are ind ...[more]