Ontology highlight
ABSTRACT:
SUBMITTER: Jones FR
PROVIDER: S-EPMC3578229 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Jones Frank R FR Gabitzsch Elizabeth S ES Xu Younong Y Balint Joseph P JP Borisevich Viktoriya V Smith Jennifer J Smith Jeanon J Peng Bi-Hung BH Walker Aida A Salazar Magda M Paessler Slobodan S
Vaccine 20110805 40
Vaccines against emerging pathogens such as the 2009 H1N1 pandemic virus can benefit from current technologies such as rapid genomic sequencing to construct the most biologically relevant vaccine. A novel platform (Ad5 [E1-, E2b-]) has been utilized to induce immune responses to various antigenic targets. We employed this vector platform to express hemagglutinin (HA) and neuraminidase (NA) genes from 2009 H1N1 pandemic viruses. Inserts were consensuses sequences designed from viral isolate seque ...[more]