Ontology highlight
ABSTRACT:
SUBMITTER: Stoppin-Mellet V
PROVIDER: S-EPMC3578873 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Stoppin-Mellet Virginie V Fache Vincent V Portran Didier D Martiel Jean-Louis JL Vantard Marylin M
PloS one 20130221 2
Microtubules (MTs) are highly dynamical structures that play a crucial role in cell physiology. In cooperation with microtubule-associated proteins (MAPs), MTs form bundles endowing cells with specific mechanisms to control their shape or generate forces. Whether the dynamics of MTs is affected by the lateral connections that MAPs make between MTs during bundle formation is still under debate. Using in vitro reconstitution of MT bundling, we analyzed the dynamics of MT bundles generated by two p ...[more]