Ontology highlight
ABSTRACT:
SUBMITTER: Shentu XC
PROVIDER: S-EPMC3580246 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Shentu Xing-Chao XC Zhao Su-Juan SJ Zhang Li L Miao Qi Q
International journal of ophthalmology 20130218 1
<h4>Aim</h4>To identify the genetic defect in a Chinese family with bilateral progressive childhood posterior cataract.<h4>Methods</h4>A two-generation family was recruited in this study. Family history and clinical data were recorded. All reported candidate genes associated with congenital posterior cataract were screened by direct DNA sequencing.<h4>Results</h4>All affected individuals presented posterior opacities in the lens. Direct sequencing of the candidate genes showed a heterozygous c. ...[more]