Ontology highlight
ABSTRACT:
SUBMITTER: Kim C
PROVIDER: S-EPMC3582849 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Kim Chihwa C Schneider Gabriela G Abdel-Latif Ahmed A Mierzejewska Kasia K Sunkara Manjula M Borkowska Sylwia S Ratajczak Janina J Morris Andrew J AJ Kucia Magda M Ratajczak Mariusz Z MZ
Stem cells (Dayton, Ohio) 20130301 3
Ceramide-1-phosphate (C1P) is a bioactive lipid that, in contrast to ceramide, is an antiapoptotic molecule released from cells that are damaged and "leaky." As reported recently, C1P promotes migration of hematopoietic cells. In this article, we tested the hypothesis that C1P released upon tissue damage may play an underappreciated role in chemoattraction of various types of stem cells and endothelial cells involved in tissue/organ regeneration. We show for the first time that C1P is upregulate ...[more]