Ontology highlight
ABSTRACT:
SUBMITTER: Warrington SJ
PROVIDER: S-EPMC3583042 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Warrington Samantha J SJ Strutt Helen H Strutt David D
Development (Cambridge, England) 20130130 5
Polarised tissue elongation during morphogenesis involves cells within epithelial sheets or tubes making and breaking intercellular contacts in an oriented manner. Growing evidence suggests that cell adhesion can be modulated by endocytic trafficking of E-cadherin (E-cad), but how this process can be polarised within individual cells is poorly understood. The Frizzled (Fz)-dependent core planar polarity pathway is a major regulator of polarised cell rearrangements in processes such as gastrulati ...[more]