Ontology highlight
ABSTRACT:
SUBMITTER: Molleston JP
PROVIDER: S-EPMC3583208 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Molleston Jean P JP Mellman William W Narkewicz Michael R MR Balistreri William F WF Gonzalez-Peralta Regino P RP Jonas Maureen M MM Lobritto Steven J SJ Mohan Parvathi P Murray Karen F KF Njoku Dolores D Rosenthal Philip P Barton Bruce A BA Talor Monica V MV Cheng Irene I Schwarz Kathleen B KB Haber Barbara A BA
Journal of pediatric gastroenterology and nutrition 20130301 3
<h4>Objectives</h4>Autoantibodies were studied in a well-characterized cohort of children with chronic hepatitis C during treatment with pegylated interferon and ribavirin to assess the relation with treatment and development of autoimmune disease.<h4>Methods</h4>: A total of 114 children (5-17 years), screened for the presence of high-titer autoantibodies, were randomized to pegylated interferon with or without ribavirin. Anti-nuclear, anti-liver-kidney-microsomal, anti-thyroglobulin, anti-thyr ...[more]