Aplysqualenols A and B: Squalene-Derived Polyethers with Antitumoral and Antiviral Activity from the Caribbean Sea Slug Aplysia dactylomela.
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SUBMITTER: Vera B
PROVIDER: S-EPMC3583239 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
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Aplysqualenols A and B: Squalene-Derived Polyethers with Antitumoral and Antiviral Activity from the Caribbean Sea Slug <i>Aplysia dactylomela.</i>
Vera Brunilda B Rodríguez Abimael D AD Avilés Edward E Ishikawa Yasuyuki Y
European journal of organic chemistry 20090916 31
The novel bromotriterpene polyethers aplysqualenol A (<b>1</b>) and aplysqualenol B (<b>2</b>) have been isolated from the Caribbean sea slug <i>Aplysia dactylomela</i> collected in Puerto Rico, and their structures and relative configurational assignments established from spectroscopic data aided by quantum mechanical calculations of NMR chemical shifts. Although both these compounds may be conceived as polyoxycyclic derivatives of the C30 squalene skeleton, remarkably <b>1</b> and <b>2</b> pos ...[more]
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