The maximum standardized uptake value of 18 F-FDG PET scan to determine prognosis of hormone-receptor positive metastatic breast cancer.

ABSTRACT:

Background

Whether PET scan maximum standard uptake value (SUVmax) could differentiate luminal A from luminal B and help predict the survival of metastatic breast cancer (MBC) patients with luminal subtype is still unknown and need to be investigated.

Methods

305 MBC patients with luminal subtypes were screened with PET/CT. Eligible patients were prospectively followed up.

Results

In total, 134 patients were eligible for this study. SUVmax was significantly related to the number of metastatic sites and presence of visceral metastasis on univariate analysis. SUVmax could not effectively differentiate patients with luminal A from luminal B subtype. Although luminal subtype at diagnosis could predict the relapse-free interval, it could not predict progression-free surviv

SUBMITTER: Zhang J 

PROVIDER: S-EPMC3583732 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature