Ontology highlight
ABSTRACT:
SUBMITTER: Armeanu-Ebinger S
PROVIDER: S-EPMC3583930 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Armeanu-Ebinger Sorin S Hoh Alexander A Wenz Julia J Fuchs Joerg J
Oncoimmunology 20130101 1
Hepatoblastoma (HB) is the most common liver cancer in children. Recurrence of HB after chemotherapy and surgery is frequent among high-risk patients and is associated with chemoresistance. Immunotherapy may improve poor treatment outcomes in HB patients. Cytotoxic leukocytes of the innate and adaptive immune system including different populations of cytotoxic T cells play a major role in fighting developing tumors. In this setting, monoclonal antibodies may be employed to specifically direct im ...[more]