Ontology highlight
ABSTRACT:
SUBMITTER: Setlur SR
PROVIDER: S-EPMC3584328 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Setlur Sunita R SR Ihm Chunhwa C Tchinda Joelle J Shams Soheil S Werner Lillian L Cho Eun Kyung EK Thompson Christina C Phillips Kimberly K Rassenti Laura Z LZ Kipps Thomas J TJ Neuberg Donna D Freedman Arnold S AS Lee Charles C Brown Jennifer R JR
British journal of haematology 20100831 4
Approximately 10% of patients with chronic lymphocytic leukaemia (CLL) have a family history of the disease or a related lymphoproliferative disorder, yet the relationship of familial CLL to genomic abnormalities has not been characterized in detail. We therefore studied 75 CLL patients, half familial and half sporadic, using high-resolution array comparative genomic hybridization (CGH), in order to better define the relationship of genomic abnormalities to familial disease and other biological ...[more]