Intrinsic protein disorder in human pathways.
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ABSTRACT:
SUBMITTER: Fong JH
PROVIDER: S-EPMC3584708 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Publications
Intrinsic protein disorder in human pathways.
Fong Jessica H JH Shoemaker Benjamin A BA Panchenko Anna R AR
Molecular bioSystems 20111020 1
We analyze human-specific KEGG pathways trying to understand the functional role of intrinsic disorder in proteins. Pathways provide a comprehensive picture of biological processes and allow better understanding of a protein's function within the specific context of its surroundings. Our study pinpoints a few specific pathways significantly enriched in disorder-containing proteins and identifies the role of these proteins within the framework of pathway relationships. Three major categories of r ...[more]
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