Ontology highlight
ABSTRACT:
SUBMITTER: Bason C
PROVIDER: S-EPMC3585221 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Bason Caterina C Lorini Renata R Lunardi Claudio C Dolcino Marzia M Giannattasio Alessandro A d'Annunzio Giuseppe G Rigo Antonella A Pedemonte Nicoletta N Corrocher Roberto R Puccetti Antonio A
PloS one 20130228 2
Type 1 diabetes is characterized by autoimmune destruction of pancreatic beta cells. The role played by autoantibodies directed against beta cells antigens in the pathogenesis of the disease is still unclear. Coxsackievirus B infection has been linked to the onset of type 1 diabetes; however its precise role has not been elucidated yet. To clarify these issues, we screened a random peptide library with sera obtained from 58 patients with recent onset type 1 diabetes, before insulin therapy. We i ...[more]